Spotlight looks in detail at the cases of two of the missing children.
Both are Somali girls who abruptly disappeared weeks after arriving in Belfast, almost seven years apart.
All the missing children were classed as “separated children”.
Separated children are children outside their country of origin and separated from their parents or legal guardian. The term can also include unaccompanied asylum seeking children and trafficked children.
Freedom of Information requests submitted by BBC Spotlight show that 49 separated children presented to health trusts across Northern Ireland since 2010.
Children from Syria, Somalia, Afghanistan, Vietnam and North Korea are among those who have made it to Northern Ireland without their families.
The Health and Social Care Board have said no children have gone missing since 2014.
BBC Spotlight has been trying to get exact details of how many children have gone missing but the data has been difficult to obtain from the authorities.
According to the Health and Social Care Board, eight children have gone missing since 2005 and remain missing.
